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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Free Radic Biol Med. 2011 Oct 20;52(1):46–58. doi: 10.1016/j.freeradbiomed.2011.10.441

Table 1.

Major mammalian antioxidants discussed in this review

Antioxidant enzyme Abbreviation used Function Family members
Superoxide dismutase Sod Conversion of superoxide to oxygen and H2O2 Sod1 (CuZnSod), Sod2 (MnSod), Sod3 (ECSod)
Catalase Cat Conversion of H2O2 to oxygen and water Cat
Glutathione peroxidase GPx Conversion of hydroperoxides to water and alcohols GPx1-8
Peroxiredoxin Prdx Reduction of hydroperoxides, peroxinitrite Prdx1-6
Thioredoxin Trx Reduction of protein cysteine-thiol disulfide bonds Trx1, Trx2
Methionine sulfoxide reductase Msr Reduction of methionine sulfoxide to methionine MsrA, MsrB1, MsrB2, MsrB3