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. Author manuscript; available in PMC: 2013 Jan 3.
Published in final edited form as: Neuroscience. 2011 Nov 4;200C:31–41. doi: 10.1016/j.neuroscience.2011.10.047

Figure 5.

Figure 5

ACh-stimulated and nicotine-stimulated DA release from synaptosomes in six lines of α6 L9′S mice. A. For control and six α6 L9′S mouse lines, αCtxMII-sensitive (α6*-dependent) DA release from caudate/putamen (CPu) and olfactory tubercle (OT) synaptosomes was measured in response to stimulation with 0.1 μM ACh. B. For control and six α6 L9′S mouse lines, αCtxMII-sensitive (α6*-dependent) DA release from caudate/putamen (CPu) and olfactory tubercle (OT) synaptosomes was measured in response to stimulation with 0.1 μM nicotine. For (A) and (B), data are expressed as a percentage of the response from a control group (set to 100%) of mice assayed on the same day. The number of mice for ACh-stimulated and nicotine-stimulated DA release was as follows: control, n = 8; line 2, n = 8; line 5, n = 8; line 9, n = 6; line 11, n = 8; line 15, n = 8; line 29, n = 6. Data are mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001