Table I.
Potential bonding interactions between Kd and tapasin
| Kd | Tapasin | Distance between atoms (Å) | Type of interaction |
|---|---|---|---|
| ND2-N86 (α1 helix)a | OE1-E11 | 2.70 | hydrogen bond |
| OG1-T134 (α2 loop) | NH1-R187 | 3.07 | hydrogen bond |
| OG1-T134 (α2 loop) | NE2-Q189 | 3.37 | hydrogen bond |
| O-A136 (α2 loop) | NE2-Q261 | 2.99 | hydrogen bond |
| NH1-R144 (α2-1 helix) | O-P80 | 2.68 | hydrogen bond |
| NH2-R144 (α2-1 helix) | O-P80 | 3.33 | hydrogen bond |
| OE2-E222 (α3) | NH1-R333 | 2.69 | salt bridge |
| OE2-E222 (α3) | NE2-H335 | 2.70 | salt bridge |
| O-D223 (α3) | N-H334 | 2.75 | hydrogen bond |
| OD2-D227 (α3) | NE2-H334 | 2.79 | salt bridge |
a
MHC class I domain structure