Figure 2.

Relationship between rs805297 genotypes and APOM expression. (A) APOM gene expression level by rs805297 genotypes. We performed qRT-PCR using RNA from 23 RA cases. The individuals with the genotypes containing the A allele showed significantly lower level of APOM expression than those with C/C homozygote genotype. (B) Effect of the rs805297C > A on the transcriptional activity of APOM promoter in 239HEK cells. The results are represented as mean ± SD of relative luciferase activities obtained from the triplicate experiments. P-values were determined by Mann-Whitney Test.