Table 2.
Experimental pain assessment for healthy cohort and clinical cohort.
| Healthy Cohort N=56 |
Clinical Cohort N=58 |
|||
|---|---|---|---|---|
| Experimental pain | P-Value | |||
| assessment | Mean (SD) | Mean (SD) | ||
| 5th pulse at 48°C baseline | 20.35 (23.06) | 27.79 (22.18) | >0.05 | |
| post 48 hours | 20.76 (24.28) | ------ | ||
| post 96 hours | 19.24 (22.92) | ------ | ||
| 3 month after surgery | ------ | 19.72 (18.68) | ||
| 5th pulse at 50°C baseline | 24.98 (25.41) | 36.65(24.16) | <0.05 | |
| post 48 hours | 27.13 (27.74) | ------ | ||
| post 96 hours | 25.75 (26.67) | ------ | ||
| 3 month after surgery | ------ | 27.95 (22.98) | ||
| Pre CPM baseline | 19.78 (20.38) | 29.90 (22.19) | <0.05 | |
| post 48 hours | 18.59 (18.72) | ------ | ||
| post 96 hours | 18.97 (20.78) | ------ | ||
| 3 month after surgery | ------ | 20.90 (12.91) | ||
| Post CPM baseline | 9.98 (12.95) | 20.71 (19.32) | <0.05 | |
| post 48 hours | 9.83 (12.74) | ------ | ||
| post 96 hours | 9.86 (12.85) | ------ | ||
| 3 month after surgery | ------ | 14.27 (12.77) | ||
| Absolute difference CPM | 9.8 (12.43) | 9.27 (12.13) | >0.05 | |
| baseline | ||||
| post 48 hours | 8.76 (10.24) | ------ | ||
| post 96 hours | 9.11 (13.06) | ------ | ||
| 3 month after surgery | ------ | 6.70 (8.72) | ||
| Percent change CPM baseline* |
54.12% | 17.08% | <0.05 | |
| post 48 hours | 35.51% | ------ | ||
| post 96 hours | 49.91% | ------ | ||
| 3 month after surgery | ------ | 35.67% | ||
*
Reported means are based on calculation of individual percent changes.