Table 1.
The Six Outcome Variables from the Intravenous Insulin Boluses
| |
Insulin dose (IU/kg) |
|
||
|---|---|---|---|---|
| 0.01 | 0.02 | 0.04 | P value | |
| Tdecr (min) | 3.88 (0.64) | 4.00 (1.41) | 3.33 (0.58) | 0.32 |
| MRD (mmol/L/min) | 0.098 (0.010) | 0.10 (0.030) | 0.14 (0.017) | 0.027 |
| Tdecrmax (min) | 4.50 (1.41) | 4.57 (1.33) | 3.67 (1.15) | 0.74 |
| ΔCmax (mmol/L) | 0.73 (0.14) | 1.10 (0.37) | 1.57 (0.058) | <0.001 |
| Tmin (min) | 16.1 (4.6) | 18.6 (5.6) | 21.7 (7.6) | 0.46 |
| AOC0–30 (mmol/L/min) | 9.42 (3.63) | 18.51 (6.47) | 27.82 (2.48) | <0.001 |
All data are mean (SD) values.
P values are from comparisons using linear mixed-effect models.
AOC0–30, area over the curve from 0 to 30 min; ΔCmax, maximum decrease in blood glucose level; MRD, maximum rate of decrease; Tdecr, time until the first detectable decrease in blood glucose level; Tdecrmax, time until maximum rate of decrease; Tmin, time until the lowest measured blood glucose level.