Table 3.
Histomorphometric analysis at 16 wk
| Alox5+/+ control diet | Alox5+/+ high-fat diet | Alox5−/− control diet | Alox5−/− high-fat diet | |
|---|---|---|---|---|
| ObS/BS | 9.64 ± 1.07 | 12.11 ± 0.98 | 12.06 ± 1.32 | 15.93 ± 1.09 |
| N.Ob/BPm | 10.68 ± 0.96 | 12.80 ± 1.07 | 12.95 ± 1.33 | 17.15 ± 1.20a |
| OcS/BS | 5.02 ± 0.65 | 3.71 ± 0.32 | 3.46 ± 0.37 | 3.95 ± 0.44 |
| N.Oc/BPm | 1.70 ± 0.21 | 1.21 ± 0.12 | 1.03 ± 0.07 | 1.40 ± 0.12b |
Values are expressed as the mean ± sem (n = 5). ObS, Osteoblast surface; OcS, osteoclast surface.
a
P < 0.05 vs. Alox5−/− control diet.
b
P = 0.028 vs. Alox5−/− control diet.