Table 2.
Reproductive profiles on Tsc1loxP/loxP and Tsc1CKO mice
| Tsc1loxP/loxP | Tsc1CKO | P value | |
|---|---|---|---|
| Total normal ovulation oocytes | 8.7 ± 1.3 (n = 3) | 42.0 ± 1.5 (n = 3) | <0.0001 |
| Healthy oocytes (%) | 8.3 ± 1.3 (95) | 7.3 ± 0.3 (17) | 0.50 |
| Degenerated oocytes (%) | 0.3 ± 0.3 (4.2) | 34.7 ± 0.9 (83) | <0.0001 |
| Total superovulated oocytes | 37.8 ± 5.7 (n = 4) | 56.5 ± 7.6 (n = 4) | 0.10 |
| Healthy oocytes (%) | 34.3 ± 5.7 (91) | 20.8 ± 2.8 (37) | 0.08 |
| Degenerated oocytes (%) | 3.5 ± 2.0 (9.7) | 35.8 ± 5.0 (63) | <0.0001 |
| Total embryos (d 2.5) | 11.0 ± 1.0 (n = 3) | 27.0 ± 9.2 (n = 3) | 0.16 |
| Healthy embryos (%) | 10.3 ± 1.3 (94) | 6.7 ± 0.7 (25) | 0.03 |
| Degenerated embryos (%) | 0.7 ± 0.3 | 20.3 ± 9.0 (75) | 0.02 |
| Total embryos (d 3.5) | 11.0 ± 0 (n = 3) | 32 ± 5.2 (n = 4) | 0.02 |
| Healthy embryos (%) | 9.3 ± 0.3 (85) | 7.0 ± 2.0 (25) | 0.38 |
| Degenerated embryos (%) | 1.7 ± 0.3 (15) | 25.0 ± 0.1 (74) | 0.0047 |
| Implantation (embryo transfer) | 6.5 ± 1.6 (n = 3) | 0 (n = 3) |
Results are shown as mean ± sem.