Table 3.
Correlational analysis of gene expression with average daily intake and average blood ethanol concentrations for the 6 months prior to necropsy.
DLPFC |
OFC |
ACC |
||||
---|---|---|---|---|---|---|
Daily intake | BEC | Daily intake | BEC | Daily intake | BEC | |
GRIA1 FLIP | −0.00833 | −0.00835 | −0.189 | −0.233 | −0.484 | −0.553 |
GRIA1 FLOP | 0.311 | 0.276 | −0.0703 | −0.148 | −0.327 | −0.344 |
GRIA2 FLIP | 0.195 | 0.259 | −0.646 | −0.679 | −0.528 | −0.523 |
GRIA2 FLOP | 0.773 | 0.820* | 0.869* | 0.893* | 0.547 | 0.571 |
GRIA3 FLIP | 0.831* | 0.943** | 0.345 | 0.344 | 0.391 | 0.454 |
GRIA3 FLOP | 0.428 | 0.476 | 0.768 | 0.785 | 0.345 | 0.390 |
GRIA4 FLIP | 0.467 | 0.445 | 0.0481 | 0.108 | 0.438 | 0.417 |
GRIA4 FLOP | 0.840* | 0.883* | 0.732 | 0.756 | 0.626 | 0.640 |
GRIK1 | 0.562 | 0.536 | 0.186 | 0.158 | 0.239 | 0.169 |
GRIK2 | 0.628 | 0.636 | 0.189 | 0.151 | 0.145 | 0.0649 |
GRIK3 | −0.185 | −0.157 | −0.120 | −0.133 | −0.537 | −0.548 |
GRIK4 | 0.172 | 0.150 | −0.0974 | −0.129 | 0.178 | 0.127 |
GRIK5 | 0.370 | 0.373 | 0.412 | 0.386 | 0.478 | 0.417 |
PICK1 | 0.794 | 0.751 | 0.693 | 0.684 | 0.355 | 0.300 |
GRIP | −0.266 | −0.295 | −0.473 | −0.505 | 0.129 | 0.0628 |
Values expressed are Pearson correlation coefficients (r2) for the six male monkeys that consumed alcohol in the present study. *P < 0.05; **P < 0.01. Bold values highlight statistical significance of Pearson correlations.