Fig. 5.

Concentration-dependent inhibition of GHB RBC uptake by l-lactate. Closed circles, uptake of 10 mM GHB at pH 7.4 at the respective l-lactate concentration. Solid line, fitting with eq. 2. Results are from two experiments performed in triplicate. Data are presented as mean ± S.E.M. Inset displays effect of measured in vivo l-lactate concentrations (≤5 mM) on GHB transport compared to control (0 mM).