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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Biol Inorg Chem. 2011 Sep 15;17(1):123–132. doi: 10.1007/s00775-011-0836-1

Fig. 7.

Fig. 7

Effect of desipramine on p53 levels induced by platinum drugs. HCT116 cells were cultured with 50 μmol/L BBR3464, 10 μmol/L c-DDP, or 30 μmol/L oxaliplatin in the absence or presence of 40 μmol/L desipramine. p53 expression was detected by Western blotting. The graph shows averages and standard deviations from three measurements of PARP expression normalized to actin loading control. Asterisks p < 0.05 when comparing cells treated with and without desipramine, by Student’s t test