Figure 6.

Lack of effect of claudin-10a expression on oxalate and mannitol permeability. (A) We measured dilution potentials (mV) across MDCK II monolayers following a 120 to 60 mM apical NaCl dilution without and with induction of claudin-10a expression. Immunoblot confirming claudin-10a induction is shown in the inset. The data are expressed as the means ± SEM (n = 4). *P < 0.05 versus uninduced cells. (B) Despite an effect of claudin-10a on anion permeability as measured by dilution potential, oxalate and mannitol permeability remained unaffected by induction of claudin-10a. The data are expressed as the means ± SEM (n = 4).