Table 2.
Characteristicsa | Tertile 1 |
Tertile 2 |
Tertile 3 |
||||||
---|---|---|---|---|---|---|---|---|---|
Caucasians (n = 170) | African Americans (n = 102) | Pb | Caucasians (n = 197) | African Americans (n = 77) | Pb | Caucasians (n = 187) | African Americans (n = 83) | Pb | |
Age, years | 54.9 (15.4) | 52.4 (15.9) | 0.20 | 59.3 (14.2) | 54.4 (14.5) | 0.01 | 61.4 (13.4) | 56.1 (13.4) | <0.01 |
Female, % | 44.1 | 49.0 | 0.43 | 44.2 | 57.1 | 0.05 | 42.8 | 55.4 | 0.06 |
Hemodialysis % | 66.5 | 90.2 | <0.01 | 81.7 | 84.4 | 0.60 | 79.7 | 92.8 | <0.01 |
Smoking, % | 14.6 | 18.6 | 0.68 | 16.8 | 15.8 | 0.01 | 13.9 | 19.8 | 0.02 |
BMI, kg/m2 | 25.6 (4.7) | 26.1 (5.7) | 0.45 | 27.0 (6.3) | 27.0 (5.7) | 0.99 | 27.3 (7.6) | 30.6 (9.8) | <0.01 |
Systolic BP, mmHg | 148 (20) | 153 (17) | 0.03 | 150 (19) | 157 (17) | 0.01 | 147 (18) | 152 (16) | 0.07 |
Diabetes, % | 54.1 | 47.1 | 0.26 | 55.6 | 55.8 | 0.97 | 51.3 | 66.3 | 0.02 |
Prevalent CVD, % | 41.8 | 25.7 | <0.01 | 45.9 | 33.8 | 0.07 | 58.8 | 41.0 | <0.01 |
Congestive heart failure, % | 36.5 | 36.3 | 0.97 | 50.0 | 54.6 | 0.50 | 56.2 | 49.4 | 0.30 |
Comorbidity score (0 to 3, where 3 is most severe) | 1.91 (0.86) | 1.77 (0.74) | 0.18 | 1.95 (0.80) | 1.82 (0.79) | 0.20 | 2.07 (0.77) | 2.16 (0.78) | 0.39 |
Severe comorbidity, score = 3 (severe) | 32.4 | 18.6 | 0.01 | 27.9 | 23.4 | 0.44 | 33.2 | 38.6 | 0.39 |
Cholesterol, mg/dl | 191 (53) | 180 (43) | 0.09 | 193 (46) | 190 (59) | 0.66 | 186 (47) | 190 (49) | 0.50 |
CRP, mg/L | 1.2 (0.9, 1.7) | 1.3 (0.9, 1.6) | 0.98 | 3.8 (3.0, 4.6) | 3.8 (3.1, 4.5) | 0.91 | 15.3 (9.2, 24.0) | 14.6 (10.3, 21.4) | 0.66 |
IL-6, pg/ml | 2.6 (1.8, 3.9) | 2.5 (1.9, 3.6) | 0.68 | 3.9 (2.9, 5.6) | 3.7 (2.4, 5.5) | 0.78 | 8.1 (5.3, 15.7) | 5.8 (3.8, 11.4) | 0.67 |
Albumin, g/dl | 3.7 (0.4) | 3.6 (0.4) | 0.53 | 3.6 (0.4) | 3.7 (0.3) | 0.32 | 3.6 (0.4) | 3.6 (0.3) | 0.64 |
Hemoglobin, g/dl | 11.1 (1.1) | 10.7(1.3) | <0.01 | 10.8 (1.4) | 10.3 (1.3) | <0.01 | 10.6 (1.3) | 10.1 (1.3) | <0.01 |
BMI, body mass index; CVD, cardiovascular disease; CRP, C-reactive protein.
aMedian (interquartile range) for CRP, and IL-6, arithmetic mean (SD) for other continuous variables.
bBy t test or chi-squared test.