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. 2011 Dec;22(12):2279–2286. doi: 10.1681/ASN.2011030305

Table 2.

Baseline characteristics of study participants by CRP tertile and race

Characteristicsa Tertile 1
Tertile 2
Tertile 3
Caucasians (n = 170) African Americans (n = 102) Pb Caucasians (n = 197) African Americans (n = 77) Pb Caucasians (n = 187) African Americans (n = 83) Pb
Age, years 54.9 (15.4) 52.4 (15.9) 0.20 59.3 (14.2) 54.4 (14.5) 0.01 61.4 (13.4) 56.1 (13.4) <0.01
Female, % 44.1 49.0 0.43 44.2 57.1 0.05 42.8 55.4 0.06
Hemodialysis % 66.5 90.2 <0.01 81.7 84.4 0.60 79.7 92.8 <0.01
Smoking, % 14.6 18.6 0.68 16.8 15.8 0.01 13.9 19.8 0.02
BMI, kg/m2 25.6 (4.7) 26.1 (5.7) 0.45 27.0 (6.3) 27.0 (5.7) 0.99 27.3 (7.6) 30.6 (9.8) <0.01
Systolic BP, mmHg 148 (20) 153 (17) 0.03 150 (19) 157 (17) 0.01 147 (18) 152 (16) 0.07
Diabetes, % 54.1 47.1 0.26 55.6 55.8 0.97 51.3 66.3 0.02
Prevalent CVD, % 41.8 25.7 <0.01 45.9 33.8 0.07 58.8 41.0 <0.01
Congestive heart failure, % 36.5 36.3 0.97 50.0 54.6 0.50 56.2 49.4 0.30
Comorbidity score (0 to 3, where 3 is most severe) 1.91 (0.86) 1.77 (0.74) 0.18 1.95 (0.80) 1.82 (0.79) 0.20 2.07 (0.77) 2.16 (0.78) 0.39
Severe comorbidity, score = 3 (severe) 32.4 18.6 0.01 27.9 23.4 0.44 33.2 38.6 0.39
Cholesterol, mg/dl 191 (53) 180 (43) 0.09 193 (46) 190 (59) 0.66 186 (47) 190 (49) 0.50
CRP, mg/L 1.2 (0.9, 1.7) 1.3 (0.9, 1.6) 0.98 3.8 (3.0, 4.6) 3.8 (3.1, 4.5) 0.91 15.3 (9.2, 24.0) 14.6 (10.3, 21.4) 0.66
IL-6, pg/ml 2.6 (1.8, 3.9) 2.5 (1.9, 3.6) 0.68 3.9 (2.9, 5.6) 3.7 (2.4, 5.5) 0.78 8.1 (5.3, 15.7) 5.8 (3.8, 11.4) 0.67
Albumin, g/dl 3.7 (0.4) 3.6 (0.4) 0.53 3.6 (0.4) 3.7 (0.3) 0.32 3.6 (0.4) 3.6 (0.3) 0.64
Hemoglobin, g/dl 11.1 (1.1) 10.7(1.3) <0.01 10.8 (1.4) 10.3 (1.3) <0.01 10.6 (1.3) 10.1 (1.3) <0.01

BMI, body mass index; CVD, cardiovascular disease; CRP, C-reactive protein.

aMedian (interquartile range) for CRP, and IL-6, arithmetic mean (SD) for other continuous variables.

bBy t test or chi-squared test.