Table 4.

Relative hazard (95% confidence interval) of all-cause mortality comparing African Americans with Caucasians, by CRP tertile

	Overall African Americans Compared with Caucasians (Referent) (n = 816)	By CRP Tertile			*P for Linear Trend across CRP Tertiles
		Tertile 1 (n = 272)	Tertile 2 (n = 274)	Tertile 3 (n = 270)
Crude	0.46 (0.39 to 0.54)	0.53 (0.39 to 0.72)	0.45 (0.31 to 0.67)	0.39 (0.29 to 0.54)	0.05
Model 1a	0.51 (0.43 to 0.62)	0.63 (0.46 to 0.85)	0.47 (0.31 to 0.71)	0.44 (0.30 to 0.64)	0.05
Model 2b	0.61 (0.49 to 0.75)	0.90 (0.63 to 1.28)	0.56 (0.34 to 0.92)	0.48 (0.31 to 0.75)	<0.01
Model 3c	0.67 (0.53 to 0.85)	0.89 (0.61 to 1.29)	0.58 (0.35 to 0.98)	0.51 (0.33 to 0.80)	<0.01
Model 4d	0.68 (0.53 to 0.86)	1.01 (0.72 to 1.40)	0.73 (0.42 to 1.28)	0.51 (0.33 to 0.79)	<0.01

*P for linear trend test included an interaction term for race and CRP tertile and describes how the effect of CRP varies by race.

^aModel 1, adjusted for age and sex.

^bModel 2, adjusted for model 1, dialysis modality, and traditional cardiovascular disease (CVD) risk factors (smoking status, body mass index, diabetes, blood pressure, cholesterol), prevalent CVD, and congestive heart failure.

^cModel 3, adjusted for model 2 plus comorbidity score, hemoglobin, and serum albumin.

^dModel 4, adjusted for model 3 and CRP, and IL-6 levels.