Table 2. Transcripts Highly (More Than 17-Fold) Overexpressed in Neut Versus G-MDSC.
| GenBank ID | Gene symbol | Gene description | Fold change |
|---|---|---|---|
| NM_011580.2 | Thbs1 | thrombospondin 1 | 129.47 |
| NM_008176.1 | Cxcl1 | chemokine (C-X-C motif) ligand 1 | 99.08 |
| NM_013654.2 | Ccl7 | chemokine (C-C motif) ligand 7 | 90.52 |
| NM_011580.2 | Thbs1 | thrombospondin 1 | 85.15 |
| NM_008176.1 | Cxcl1 | chemokine (C-X-C motif) ligand 1 | 81.31 |
| NM_008608.2 | Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 71.26 |
| NM_008509.1 | Lpl | lipoprotein lipase | 54.85 |
| NM_008630.1 | Mt2 | metallothionein 2 | 53.48 |
| AK036786.1 | Slc7a11 | solute carrier family 7 member 11 | 52.18 |
| NM_203320.1 | Gm1960 | gene model 1960 (NCBI) | 49.69 |
| NM_019932.1 | Cxcl4 | chemokine (C-X-C motif) ligand 4 | 46.19 |
| NM_007534.1 | Bcl2a1b | B cell leukemia/lymphoma 2-related protein A1b | 42.42 |
| NM_026644.1 | Agpat4 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 39.92 |
| NM_010493.2 | Icam1 | ICAM | 39.86 |
| NM_001033450.1 | Mnda | myeloid cell nuclear differentiation antigen | 37.60 |
| AB022345.1 | Slc7a11 | solute carrier family 7 member 11 | 37.51 |
| NM_013693.1 | Tnf | TNF | 37.38 |
| NM_009421 | Traf1 | TRAF1 | 36.02 |
| NM_011521.1 | Sdc4 | syndecan 4 | 34.15 |
| NM_031168.1 | II6 | IL-6 | 33.41 |
| NM_001039701.1 | II1m | IL-1R antagonist | 29.83 |
| NM_009263.1 | Spp1 | secreted phosphoprotein 1 | 28.38 |
| NM_009112.1 | S100a10 | S100 calcium-binding protein A10 (calpactin) | 27.97 |
| NM_013671.3 | Sod2 | SOD 2, mitochondrial | 25.96 |
| AY628210.1 | Wdt2 | whn-dependent transcript 2 | 24.91 |
| NM_011338.2 | Ccl9 | chemokine (C-C motif) ligand 9 | 24.65 |
| NM_021274.1 | Cxcl10 | chemokine (C-X-C motif) ligand 10 | 24.31 |
| NM_011311.1 | S100a4 | S100 calcium-binding protein A4 | 23.35 |
| XM_488510.4 | Cspg2 | chondroitin sulfate proteoglycan 2 | 22.55 |
| NM_011580.2 | Thbs1 | thrombospondin 1 | 22.38 |
| NM_011521.1 | Sdc4 | syndecan 4 | 22.12 |
| NM_019777.2 | Ikbke | IKKε | 21.76 |
| XM_488510.4 | Cspg2 | chondroitin sulfate proteoglycan 2 | 21.73 |
| XM_132051.7 | Rhoh | ras homolog gene family, member H | 21.38 |
| NM_009917.2 | Ccr5 | chemokine (C-C motif) receptor 5 | 20.25 |
| NM_175155.3 | Sash1 | SAM and SH3 domain-containing 1 | 19.95 |
| NM_009058.1 | Ralgds | ral guanine nucleotide dissociation stimulator | 19.80 |
| NM_009829.3 | Ccnd2 | cyclin D2 | 19.65 |
| NM_026835.1 | Ms4a6d | membrane-spanning 4 domains, subfamily A, member 6D | 19.37 |
| NM_009895.2 | Cish | cytokine-inducible SH2-containing protein | 18.73 |
| NM_013671.3 | Sod2 | SOD 2 mitochondrial | 18.71 |
| NM_008690.2 | Nfkbie | NF-κB light polypeptide gene enhancer inhibitor, ε | 18.35 |
| NM_001039701.1 | Il1rn | IL-1R antagonist | 18.26 |
| NM_009829.3 | Ccnd2 | cyclin D2 | 17.16 |
NCBI, National Center for Biotechnology Information; SAM, sterile α motif; SH 3/2, Src homology 3/2.