Table 1.

Outcome Indices for Patients Treated With Scopolamine Hydrobromide^*

	Baseline Block	Block 1	Block 2
P/S group (n = 10)
CGI-I scale score (vs baseline)†
1–2	0	0	9
3	3	2	1
4	5	6	0
5–6	2	2	0
Full response (>50%)	0	0	7
Partial response (24%–49%)	0	0	3
Remission (MADRS score ≤10)	0	0	6
S/P group (n = 8)
CGI-I scale score (vs baseline)†
1–2	0	6	7
3	2	2	1
4	4	0	0
5–6	2	0	0
Full response (>50%)	0	4	4
Partial response (25%–49%)	0	2	4
Remission (MADRS score ≤10)	0	3	4

Abbreviations: CGI-I, Clinical Global Impressions–Improvement; MADRS, Montgomery-Asberg Depression Rating Scale; P/S, placebo/scopolamine; S/P, scopolamine/placebo.

^*Data are given as number of patients.

^†In the CGI-I scale, 1 indicates very much improved; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; and 6, much worse.