Table 1. Comparison of HLA-class I (-Cw) and KIR - HLA-C complex in a cohort of Saudi patients with VKH disease and control subjects.
| Controls (n=125) | VKH patients (n=30) | |||||
|---|---|---|---|---|---|---|
|
HLA-C/KIR-HLA Complex |
(N+) |
%F |
(N+) |
%F |
p-value |
OD 95%(CI) |
|
HLA-Cw* | ||||||
| HLA-C1/C1 |
26 |
20.8 |
1 |
3.3 |
0.0291 |
0.13 (0.017–1.009) |
| HLA-C1/C2 |
63 |
50.4 |
12 |
40 |
|
|
| HLA-C2/C2 |
36 |
28.8 |
17 |
56.7 |
0.0054 |
3.23 (1.42–7.33) |
|
KIR-HLA(KIR ligand) | ||||||
| KIR2DL2/3-HLA-C1 |
88 |
70.4 |
14 |
46.7 |
0.0184 |
0.367 (0.163–0.830) |
| KIR2DL1-HLA-C2 |
97 |
77.6 |
28 |
93.3 |
|
|
| KIR2DS2-HLA-C1 |
52 |
41.6 |
9 |
30 |
|
|
| KIR2DS1-HLA-C2 | 32 | 25.6 | 8 | 26.7 | ||