Table 1. Microsatellite repeat markers linked to all known USH1 loci.
| Locus | Chromosome | Gene and markers | Location (MB) | PCR primers for marker amplification |
|---|---|---|---|---|
|
USH1B |
11 |
D11S4179 |
76 |
F: GGATGTAAGAGTAACTGGCTCG |
| |
|
|
|
R: GAAAATGTTCTGCCTGAGGG |
| |
|
D11S1789 |
76.7 |
F: ACCAGGAAATTGAGAACCA |
| |
|
|
|
R: TCTGGCCCAACAGAAGT |
| |
|
D11S4079 |
76.8 |
F: CAGCAAGATCCTGTCTCAA |
| |
|
|
|
R: CTCCTTAAAGTGGGGGAGTT |
| |
|
MYO7A |
76.8–76.9 |
|
| |
|
D11S937 |
77.5 |
F: CTAATAAACAAATCCCTCTACCTCC |
| |
|
|
|
R: TAGTCAGTCAGGGACCCAAGT |
|
USH1C |
11 |
D11S902 |
17.4 |
F: CCCGGCTGTGAATATACTTAATGC |
| |
|
|
|
R: CCCAACAGCAATGGGAAGTT |
| |
|
USH1C |
17.5 |
|
| |
|
D11S4138 |
17.7 |
F: GTGCTGACCGCTCCAAGG |
| |
|
|
|
R: CCAAAGGGGTTAATAGGGGTCCA |
|
USH1D |
10 |
D10S537 |
72 |
F: CCTACTGTGCCTGGCTAGA |
| |
|
|
|
R: ATTTGGATGAAACCCACG |
| |
|
D10S606 |
73 |
F: TTTGAACCTGGGAGACG |
| |
|
|
|
R: CATGGACATTCTGCTGC |
| |
|
D10S1694 |
73.1 |
F: CCTGTCTGGCCCAGGTA |
| |
|
|
|
R: AGTAGGGGTGCTGCTTGA |
| |
|
CDH23 |
73.1–73.5 |
|
|
USH1E |
21 |
D21S1437 |
20.5 |
F: ATGTACATGTGTCTGGGAAGG |
| |
|
|
|
R: TTCTCTACATATTTACTGCCAACA |
| |
|
USH1E (locus) |
19.8–31.3 |
|
| |
|
D21S265 |
25.8 |
F: TTAAAGCAATCAATCATGG |
| |
|
|
|
R: GGGTTCTGTGAATATGGG |
|
USH1F |
10 |
D10S2537 |
55.7 |
F: AAATGGAATATGGGGTTATTAGCA |
| |
|
|
|
R: AATTATCTACATTTCCGCCACTTC |
| |
|
D10S546 |
55.7 |
F: TGTGATGACTAGAAATTCAGTTCA |
| |
|
|
|
R: ACTTCTCAATTACAGGCCCA |
| |
|
PCDH15 |
55.5–56.5 |
|
| |
|
D10S2522 |
56.3 |
F: TTTAAACACTGTCCCAACAC |
| |
|
|
|
R: TGAAGGAAAGCCAAACTTA |
|
USH1G |
17 |
D17S1301 |
70.2 |
F: AAAGAAGATGAAATTGCCATG |
| |
|
|
|
R: TAAAAAGAATGAAGGTAAAAATGTG |
| |
|
D17S785 |
71.9 |
F: ATCCCTGGAGAGTGAAAATG |
| |
|
|
|
R: AAGGCCAACCTGAAAACTAA |
| |
|
D17S801 |
72 |
F: CCTCAAACCGGACAACTATTT |
| |
|
|
|
R: CAGAGAGCAAGATCCTACCTC |
| |
|
D17S937 |
72.8 |
F: CATGGAGGGACTTGCG |
| |
|
|
|
R: TTCCCAGAACCCGGTTT |
| |
|
USH1G |
72.9 |
|
|
USH1H |
15 |
USH1H (locus) |
65.1–68.4 |
|
| |
|
D15S1015 |
65.6 |
F: TCACAGAGCGAGACCCTAT |
| |
|
|
|
R: CACAGACTCAGTTTAGACAGAAATC |
| |
|
D15S131 |
68.9 |
F: GAAAGGCACCTCATCTCG |
| R: TTAAAAACTCTGGAGCAGCG |