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. 2012 Jan 3;7(1):e28115. doi: 10.1371/journal.pone.0028115

Table 4. Factors predictive of rapid (RVR) and sustained virological response (SVR) to anti-hepatitis C virus therapy.

Univariate nonparametric analysis Multivariable analysis
RVR SVR
Factor RVR (%) P SVR (%) P Adjusted OR (CI95) P Adjusted OR (CI95) P
Plasma HCV RNA
(≤vs.>800000 IU/mL) 67.6 vs. 25.0 0.003 82.8 vs. 50.0 0.02 5.36 (1.04 – 27.81) 0.04 6.68 (1.01 – 47.08) 0.05
LDL-C mg/dL
(≥80 vs.<80) 70.0 vs. 33.3 0.02 88.9 vs. 47.4 0.008 3.08 (0.67 – 14.05) 0.14 3.31 (0.45 – 24.33) 0.23
Cirrhosis
(no vs. yes) 60.6 vs. 40.0 0.12 74.2 vs. 62.5 0.30 2.51 (0.51 – 12.23) 0.25
Use of TDF vs. ABV 54.5 vs. 60.0 0.49 72.4 vs. 87.5 0.35 n.a. n.a.
IL28B
(CC vs. CT/TT) 43.5 vs. 42.1 0.26 63.2 vs. 68.4 0.50 n.a. n.a.
Treatment exposition
(≥80% vs.<80%) n.a. 81.6 vs. 40.0 0.07 n.a. 7.81 (0.37 – 161.4) 0.18

TDF: tenofovir. ABV: abacavir. n.a.: not applicable.