Skip to main content
. 2012 Jan 3;7(1):e28918. doi: 10.1371/journal.pone.0028918

Table 1. Early RA patient baseline demographics and associations with response to steroid/methotrexate therapy.

Entire Cohort NR MOD/GOOD NR vs. MOD/GOOD
n = 73 n = 11 n = 31 p value
Gender (% women) 69 91 64 P = 0.03 (‡)
Age (median years) 51 59 48 P = 0.071 (φ)
Smoking (% ever smoked) 45.7 66 38.4 P = 0.245 (‡)
Smoking (% current smokers) 25.7 22.2 26.9 P = 1.0 (‡)
CCP titre (mean) 204 229 194 P = 0.539 (φ)
CCP positive (%) 86 90 84 P = 0.7448 (‡)
RF titre (mean) 145 192 127 P = 0.156 (φ)
RF positive (%) 80 80 80 P = 1.00 (‡)
DAS28ESR baseline 5.6 5.20 5.74 P = 0.44 (φ)
CD16 expression (mean MFI) 15.13 21.08 13.16 P = 0.0009 (φ)

A cohort of early RA patients (n = 73) were recruited for investigation. Baseline characteristics of the cohort is summarised in column [Entire cohort]. Patients with EULAR response data at week 14 post-initiation of therapy (n = 42) were furthermore split into non-responders [NR] or moderate/good responders [MOD/GOOD] and baseline characteristics in each subgroup analysed separately. Statistically significant differences between the two EULAR response subgroups [NR vs. MOD/GOOD] were examined. (‡) fishers statistical test (φ) mann-whitney U test.