Figure 5. Effect of blocking of integrins and adhesion molecules on the migratory and adhesive properties.

(A) In vitro migration of expanded control and inhibitor-treated HSPCs to SDF1 was not affected by blocking of the integrins alone. Data are represented as mean ± standard deviation of three experiments, *p<0.05, **p<0.01, ***p<0.01. (B) However, the blocking of integrins and adhesion molecules reduced the in vitro adhesive interaction of expanded HSPCs to a higher extent. Data are represented as mean ± standard deviation of three experiments, *p<0.05, **p<0.01.