Figure 9. The effects of vitamin A precursors and metabolites on M. tb. complex.
ß-carotene, the precursor to vitamin A, exhibits no inhibition at the doses studied. Both Retinoic acid and 13-cis Retinoic acid result in dose dependent inhibition on our avirulent strain of M. tb. There is no comparable inhibition against Bacillus Calmette-Guerin (BCG).
