Table 3. Effects of continuous erythropoietin receptor activator on plasma levels of pro-inflammatory cytokines at 24 h after cecal ligation and puncture.
Variable | Control | CLP | CLP+CERA |
IL-1β (pg/ml) | 50±12 | 985±399 | 526±193 |
TNF-α (pg/ml) | 54±12 | 62±7 | 37±10 |
IFN-γ (pg/ml) | 522±240 | 1613±631 | 1118±652 |
IL-2 (pg/ml) | 36±8 | 74±18 | 29±10 |
IL-6 (pg/ml) | 291±65 | 532±80* | 237±44 |
IL-10 (pg/ml) | 96±0 | 527±211 | 348±96 |
CLP, cecal ligation and puncture; CERA, continuous erythropoietin receptor activator; IL, interleukin; TNF-α, tumor necrosis factor alpha; IFN-γ, interferon gamma.
*p<0.05 vs. CLP+CERA.