Table 1. Influence of long CAG and age on cerebral gray matter.
Region | MNI coordinates (peak) | P values | |
voxel level (corrected for ROI) | voxel level uncorrected | ||
Primary endpoint: combined effect of long CAG and its interaction with age | |||
(Contrast weights: long CAG×age, 1; age, 0; sex, 0) | |||
Pallidum L | −17 −8 −3 | 0.007 | 8.4×10−6 |
Pallidum R | 20 −12 2 | 0.11 | 0.0003 |
Secondary endpoint: main effect of long CAG | |||
(Contrast weights: long CAG, 1; age, 0; sex, 0) | |||
Pallidum L | −17 −8 −3 | 0.02 | 4.4×10−5 |
Pallidum R | 18 −5 −2 | 0.8 | 0.037 |
Secondary endpoint: effect of interaction of long CAG and age | |||
(Contrast weights: long CAG×age, 1; CAG, 0; age, 0; sex, 0) | |||
Pallidum L | −20 0 −6 | 0.2* | 0.0005 |
Pallidum R | 21 −11 0 | 0.08* | 0.0001 |
Note. L, left; R, right;
*corrected P value at the set level, 0.023.