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. 2011 Mar 21;33(4):849–860. doi: 10.1002/hbm.21252

Figure 4.

Figure 4

The local functional connectivity density (lFCD) in the brain was evaluated for (A) 336 women (25.5 ± 10.0 years old, mean ± SD) and (B) 225 age‐matched men (26.4 ± 9.7 years old; age effect: P = 0.16, t‐test) using FCDM [Tomasi and Volkow,2010]. The functional connectivity hubs (regions densely connected to other brain regions; red) were bilaterally located in the posterior cingulate/ventral precuneus, inferior parietal cortex, and cuneus. The lFCD was 13.7% ± 7.8% higher (C; ROI t‐tests) and proportional (D; R = 0.89, ROI linear correlation) for women than for men across all cortical and subcortical ROI (0.73‐ml cubic ROIs centered at the MNI coordinates listed in Table II).