Table 1.
Outcome Category | |||||||||
---|---|---|---|---|---|---|---|---|---|
A. Mortality Based | |||||||||
Criterion | All-Cause Mortality (age < 75) | CHD Mortality (age 45 to 74) | Alcohol-Related Mortality (age 45 to 74) | Total Cancer Mortality (age 45 to 74) | Healthy Life Expectancy at Birth | B. Hospitalizations (for Condition of Interest) | C. Natality (LBW rate) | D. Total Cancer Incidence (age < 75) | E. Mental Health and Well-being |
1. Epidemiological | |||||||||
Completeness and accuracy of reporting | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Clear relevance to known social determinants of health | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ? |
Reversibility/sensitivity to intervention | ? (see text) | ? (see text) | ? (see text) | ? (see text) | ? (see text) | ? (see text) | ✗ (see text) | ? (see text) | ? (see text) |
Avoidance of reverse causation | ✓ | ✓ | ✗ (see text) | ? | ✓ | ? (if chronic disability precedes admission) | ✓ | ✓ | ? (see text) |
Statistical appropriateness (e.g., use of RII, lumping of heterogeneous outcomes) | ✓ | ✓ | ✗ (use of RII) | ✗ (lumping all cancer sites) | ✓ | ✓ | ✓ | ✗ (lumping all cancer sites) | ✓ |
2. Communication | |||||||||
Clarity for nonscientists | ✓ | ✓ | ✓ | ✗ (obscures cancer sites’ mixed picture) | ? | ? (for acute CHD) | ✗ | ✗ (obscures cancer sites’ mixed picture) | ? (what does it mean?) |
Unintended side effects | ✓ | ✗ (RII trend message) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ? |
Notes: ✓= no concerns /meets criterion; ✗= major concerns /criterion not met; ?= uncertain.