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[TF] = 15 fmol/cm2, shear rate 500 s−1. (A) No fXI and near-wall platelet count (#/μL) 250,000 (solid) or 750,000 (dashed). Plots of [Plt-VIIIa:IXa] and [fIIa] versus time. (B and C) Near-wall platelet count 750,000. (B) [fIIa] versus [TF] after 10 min and 20 min with NfXI (solid) and with no fXI (dashed). (C) [Plt-VIIIa:IXa], [Plt-Va:Xa], and [fIIa] versus time with NfXI (solid) and with no fXI (dashed). (A and C, vertical lines) When platelets covered 99% of the SE.
