TABLE 10.

Drugs that have been reported to prolong the QT interval or induce torsades de points (potential interaction with grepafloxacin and sparfloxacin)

Class	Drugs
Antiarrhythmics
Class Ia	Disopyramide, procainamide, quinidine
Class III	Amiodarone, bretylium, sotalol
Antimicrobials	Erythromycin, trimethoprim/sulfamethoxazole
Antihistamines	Astemizole, terfenadine
Antimalarials or antiprotozoals	Chloroquine, halofantrine, mefloquine, pentamidine, quinine
Prokinetic agents	Cisapride
Psychoactive agents	Chloral hydrate, haloperidol, lithium, phenothiazines, pimozide, tricyclic antidepressants
Others	Amantadine, probucol, tacrolimus, vasopressin

Adapted from reference 249