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Expression of caspase-3, caspase-9, Bcl-2, Bax, cyclin D1 and cyclin E in MIA PaCa-2 and BxPC-3 cells in response to β-adrenoceptor antagonists. A negative control group is also included. The expression of the respective proteins in the whole cell lysates was examined by Western blotting. β-adrenoceptor antagonists increased the level of caspase-3, caspase-9, and Bax, while they negatively affected Bcl-2, cyclin D1, and cyclin E. *P < 0.05 when compared with controls.
