Figure 12.

Exposure of residues to the exterior of the MEPE protein. Plot of the ASA ratio calculated between the side-chain and the 'random coil' value of each residue. Sites with a ratio above 50% (yellow box) are considered to be exposed to the outside of the protein whereas sites under 20% are considered to be buried (pink box). Sites under positive selection in both gene and protein-level analyses are marked with the red dots (double) and sites showing selection in at least one of the analysis is represented as black dots (single).