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H3R activation with imetit (100 nM; 30 min) attenuates the expression of AT1R in PC12-H3 cells. Prevention by H3R blockade with CBP (50 nM) is shown. Top, representative Western blot analysis. Bottom, quantification. Bars are means ± S.E.M. (n = 3–6). *, P < 0.05 from control; ##, P < 0.01 from imetit + CBP by ANOVA and Bonferroni's multiple test.
