Table 2.

Gene expression of IL-1β, IL-6, TNF-α, CD11B, MMP-9 and GFAP after 2 h of tMCAO and 24 h post-reperfusion

	Vehicle		Solulin
Gene	Contralateral [%]	Ipsilateral [%]	Contralateral [%]	Ipsilateral [%]
IL-1β	100	1165.5 ± 1522.1	46.6 ± 42.8	242.7 ± 443.4
IL-6	100	775.2 ± 724.4	26.1 ± 22.2	411.7 ± 550.6
TNF-α	100	206.2 ± 278.9	86.1 ± 92.4	83.9 ± 56.9
MMP-9	100	257.6 ± 131.1	41.9 ± 46.5	201.6 ± 97.1
CD11B	100	236.2 ± 56.1	86.6 ± 85.5	119.6 ± 102.8
GFAP	100	108.4 ± 69.5	71.7 ± 89.7	87.1 ± 89.7

Gene expression of three consecutive coronal sections of TTC-stained hemispheres. The contralateral non-infarcted hemispheres of the vehicle-treated group acted as internal controls. Values of these hemispheres were therefore set to 100%. All other values (infarcted hemisphere vehicle-treated group, infarcted and non-infarcted hemisphere of the Solulin cohort) were expressed as percentages of the latter. RT-PCR values were normalized to the housekeeping gene HPRT and cyclophilin A. All mRNA levels are given as means ± SD.