Table 1.
Characteristic (mean ± SD) | APOE-4 NC | APOE-4 | P | APOE-4 NC partial correlation with age | APOE-4 partial correlation with age |
Age, y | 63.8 ± 8.3 | 60.8 ± 9.7 | 0.22 | ||
Age range | 45–76 | 43–78 | |||
No. (males/females) | 30 (10/20) | 25 (12/13) | |||
Education, y | 16.7 ± 1.8 | 17.5 ± 3.3 | 0.33 | ||
Family history, yes/no | 21/9 | 16/9 | |||
MMSE, score range 0–30 | 29.4 ± 0.9 | 28.6 ± 1.2 | 0.01* | r = −0.41, P = 0.07 | r = −0.14, P = 0.55 |
WMS LM delay, 0–50 | 29.1 ± 7.1 | 27.1 ± 9.2 | 0.45 | r = −0.09, P = 0.66 | r = −0.45, P = 0.038* |
Buschke CLTR, 0–144 | 56.7 ± 39.7 | 57.8 ± 34.2 | 0.92 | r = −0.16, P = 0.44 | r = −0.36, P = 0.1 |
Rey-O delay, 0–36 | 12.9 ± 7.2 | 13.8 ± 7.1 | 0.68 | r = −0.03, P = 0.87 | r = −0.57, P = 0.005* |
WMS VP, 0–32 | 22.3 ± 7.4 | 20.6 ± 8.2 | 0.49 | r = −0.17, P = 0.38 | r = 0.05, P = 0.8 |
WAIS digit span | 17.7 ± 3.6 | 18.1 ± 3.1 | 0.65 | r = 0.21, P = 0.29 | r = 0.1, P = 0.65 |
Partial correlations with age were controlled for sex, years of education, and family history of dementia. Buschke CLTR, Buschke–Fuld selective reminding test, consistent long-term retrieval section; MMSE, mini-mental state examination; NC, noncarriers; Rey-O delay, Rey–Osterrith Complex Figure, delayed recall; WAIS digit span, Wechsler Adult Intelligence Scale 3, digit span; WMS LM delay, Wechsler memory scale, logical memory delayed recall portion; WMS VP, Wechsler memory scale, verbal paired associations II. *P < 0.05.