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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Nat Genet. 2011 Oct 9;43(11):1108–1113. doi: 10.1038/ng.959

Figure 1.

Figure 1

Manhattan plot of results of Cochran-Armitage (CA) trend test stratified by geographic region, with -log10 p-values shown. The solid horizontal line indicates a p-value of 10−5. Markers within 50kb of a SNP associated with melanoma are marked in black for those identified in a previous GWA and replicated here and marked in red if first identified in the current study. The y-axis is truncated at p=10−15, although three SNPs in the MC1R region have stronger p-values, up to 2.7×10−27, as signified by the box and arrow.