Table 2.
IloProst
|
Placebo
|
Treatment Effect1 |
|||||||
---|---|---|---|---|---|---|---|---|---|
Baseline | 6-Month | Change | Baseline | 6-Month | Change | Difference | 95% CI | P-Value | |
All Completers2 | |||||||||
All Biopsies | |||||||||
Average | 2.64 | 2.41 | −0.23 | 2.56 | 2.54 | −0.02 | −0.15 | (−0.39, 0.09) | 0.210 |
Worst | 4.25 | 3.85 | −0.40 | 3.91 | 4.14 | 0.23 | −0.43 | (−0.84, −0.03) | 0.038 |
Dysp. Index | 34.97 | 27.27 | −7.70 | 34.23 | 33.32 | −0.92 | −5.97 | (−13.28, 1.33) | 0.112 |
Former Smokers3 | |||||||||
All Biopsies | |||||||||
Average | 2.12 | 1.73 | −0.39 | 2.07 | 2.11 | 0.04 | −0.41 | (−0.71, −0.11) | 0.010 |
Worst | 3.59 | 2.83 | −0.76 | 3.11 | 3.68 | 0.57 | −1.10 | (−1.76, −0.45) | 0.002 |
Dysp. Index | 20.81 | 10.90 | −9.91 | 22.90 | 24.60 | 1.70 | −12.45 | (−20.98, −3.92) | 0.006 |
Current Smokers4 | |||||||||
All Biopsies | |||||||||
Average | 3.13 | 3.05 | −0.07 | 2.93 | 2.87 | −0.06 | 0.06 | (−0.30, 0.42) | 0.743 |
Worst | 4.87 | 4.81 | −0.06 | 4.51 | 4.49 | −0.03 | 0.12 | (−0.36, 0.60) | 0.621 |
Dysp. Index | 48.22 | 42.58 | −5.64 | 42.81 | 39.91 | −2.90 | −0.33 | (−11.70, 11.05) | 0.955 |
Adjusted for baseline level of the outcome variable plus smoking status.
N = 60 (iloprost), N = 65 (placebo).
N = 29 (iloprost), N = 28 (placebo).
N = 31 (iloprost), N = 37 (placebo).