Fig. 2.
Whole-cell currents (INa, Itot, Iamil) in principal cells of cortical collecting ducts (CCDs) from rats treated with aldosterone (12 μg/day) or dexamethasone (24 μg/day). Top and middle: current traces for steps to different voltages from 0 mV in the absence (top) and presence (middle) of 10−5 M amiloride. Bottom: current-voltage relationships. In the case of the aldosterone-treated cell, the amiloride-sensitive current is plotted as the difference in current in the absence and presence of the drug.