Table 3.

Levels of VEGF, IGF-1, and HGF in mouse serum

Injected Cells	Injury	VEGF, pg/ml	IGF-1, pg/ml	HGF, pg/ml
BMC	Sham	6.1 ± 1.6	573.2 ± 83.7	503.6 ± 92.8
Treated cells	IRI 1 day	38.6 ± 5.7*	1,142.7 ± 228.4*	1,659.6 ± 164.5*
	IRI 3 days	41.8 ± 6.2*	1,173.7 ± 157.7*	1,704.1 ± 223.8*
BMC	IRI 1 day	7.2 ± 2.6	658.6 ± 93.3	774.4 ± 108.0
	IRI 3 days	7.6 ± 2.2	613.7 ± 101.2	676.1 ± 103.6

Values are mean ± SE; n = 4/group. Sera obtained from mice injected with treated cells or with untreated bone marrow cells (BMC) were examined for levels of VEGF, IGF-1, and HGF at 1 and 3 days post-renal ischemia-reperfusion injury (IRI) or sham operation. Note superphysiological concentrations of circulating VEGF, IGF-1, and HGF in mice injected with treated cells compared with that of untreated BMC injection at 1 or 3 days post-ischemic injury and -cell injection.

^*P < 0.05.