Table 4.
Univariate (ρ) and multivariate (β) correlations between PON1 activity and study population characteristics
Variable (n = 18) | Univariate | Multivariate | ||
---|---|---|---|---|
ρ | p value | β | p value | |
Age | -0.52 | 0.03 | -0.28 | 0.3 |
Sex | 0.08 | 0.8 | ||
Weight | -0.33 | 0.18 | ||
Body mass index | -0.43 | 0.07 | ||
Overall cholesterol | 0.08 | 0.7 | ||
LDL-cholesterol | 0.01 | 1.0 | ||
HDL-cholesterol | 0.63 | 0.005 | 0.52 | 0.04 |
Triglyceride | -0.24 | 0.33 | ||
Insulin | 0.11 | 0.65 | ||
Glucose | -0.17 | 0.5 | ||
HOMA-IR | 0.03 | 0.9 | ||
hsCRP | -0.36 | 0.14 | ||
Arylesterase | 0.61 | 0.008 | -0.05 | 0.8 |
Rest-MBF | 0.03 | 0.9 | ||
Stress-MBF | 0.15 | 0.5 | ||
MFR | 0.48 | 0.04 | 0.34 | 0.2 |
CPT-MBF | -0.18 | 0.47 | ||
MBF difference CPT-rest | -0.17 | 0.5 |
Relations between variables were assessed using non-parametric Spearman's correlation coefficients (ρ). Independent relations were assessed using multivariate regression analysis (β). PON1, paraoxonase 1; LDL, low-density lipoprotein; HDL, high-density lipoprotein; HOMA-IR, homeostasis model assessment- insulin resistance; hsCRP, high sensitivity C-reactive protein; MBF, myocardial blood flow; MFR, myocardial flow reserve; CPT, cold pressor test.