Figure 3.
Protein kinase C isoform assay of NHBE cells exposed to 100mM alcohol for 1, 3, 6, and 24 hr time periods. The vertical axis represents the fold activity change (SEM) of PKC activity in of NHBE cells within each exposure group (n=3). Alcohol exposure for 24 hrs caused a significant (**P ≤ 0.001) increase in the PKCα activity. A significant increase was also observed in PKCζ at 6 (*P ≤ 0.01). This result indicates that alcohol induces increases in PKCα and PKCζ.