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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Cancer Res. 2011 Nov 9;72(1):282–293. doi: 10.1158/0008-5472.CAN-11-2866

Figure 2. MLN4924 alters cell cycle progression and induces apoptosis.

Figure 2

Cells were treated with MLN4924 at 100 nM for 24 hrs (A-C) or up to 48 hrs (D), alone or in combination with radiation (6 Gy), followed by FACS analysis for cell cycle profiling (A), cell cycle distribution (B), cell population with >4N DNA content (C), and sub-G1 population for apoptosis (D). Shown is mean ± SEM, (n = 3): *, p<0.05. One representative result is shown for (A).