Table 1.

Univariate survival analysis

Variable	HR	95% CI	P value
Overall survival
Age (continuous)	1.04	1.00–1.08	0.031
Involved margin	1.62	0.73–3.56	0.233
Maximal lesion size
Size (continuous)	1.02	0.96–1.09	0.484
>1.5 versus ≤1.5 cm	1.28	0.56–2.92	0.565
No. of nodes
2–3 nodes versus 1 node	1.03	0.38–2.83	0.949
≥4 nodes versus 1 node	5.13	2.35–11.20	<0.001
STM	3.25	1.63–6.49	0.001
ENSa	2.59	1.30–5.16	0.007
Adjuvant radiotherapya	0.72	0.33–1.57	0.405
Disease-free survival
Age	1.02	0.99–1.04	0.220
Involved margin	2.18	1.20–3.96	0.010
Maximal lesion size
Size (continuous)	1.02	0.98–1.07	0.390
>1.5 versus ≤1.5 cm	1.40	0.73–2.67	0.310
No. of nodes
2–3 nodes versus 1 node	1.73	0.84–3.57	0.135
≥4 nodes versus 1 node	4.94	2.51–9.73	<0.001
STMa	2.42	1.42–4.14	0.001
ENSa	2.01	1.17–3.45	0.012
Adjuvant radiotherapy	0.79	0.42–1.50	0.471

^aDifferent reference categories for STM and ENS mean hazards are not comparable