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Fractional concentrations of oxycodone (white bars) and noroxycodone (black bars) at the last time point (4 h) in hepatocyte incubations from 3 day (A), 2 month (B), 5 month (C), 4 year (D), and adult (E) donors. Bars represent mean ± SD (single experiment in duplicate). KTZ, ketoconazole.
