Table 3. Cell death rate of each drug according to treatment response and liver resection in ATP-CRA-based chemotherapy.
|
Treatment response
|
Liver resection
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
CR/PR
|
SD/PD
|
Yes
|
No
|
|||||||
| Drug | N | CDR (%) | N | CDR (%) | P-value | N | CDR (%) | N | CDR (%) | P-value |
| 5-Fluorouracil | 15 | 34.5 | 16 | 26.7 | 0.026 | 11 | 36.2 | 20 | 27.3 | 0.040 |
| Second drug | ||||||||||
| All | 15 | 38.1 | 16 | 25.7 | 0.001 | 11 | 39.9 | 20 | 27.2 | 0.008 |
| Oxaliplatin | 8 | 41.0 | 12 | 24.5 | 0.013 | 7 | 41.6 | 13 | 25.5 | 0.033 |
| Irinotecan | 7 | 34.8 | 4 | 26.6 | 0.032 | 4 | 37.0 | 7 | 28.9 | 0.035 |
Abbreviations: ATP-CRA=adenosine triphosphate-chemotherapy response assay; CDR=cell death rate; CR=complete response; PD=progressive disease; PR=partial response; SD=stable disease.