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. 2011 Dec 1;106(1):92–98. doi: 10.1038/bjc.2011.538

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Copyright © 2012 Cancer Research UK

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Conjugation of tumour lysates to VLP negates their inhibitory effects on DC cytokine/chemokine production. Bar graphs represent (A) IL-12p70, (B) CCL5, (C) IL-6 and (D) TNF-α produced by DC after pulsing with lysate, VLP-lysate or left unpulsed, before the addition of OK432 or no adjuvant. Data represent mean±s.d. for six experiments. ^*Denotes statistical significance (P<0.05) between lysate-pulsed and unpulsed DC.