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. 2011 Dec 1;106(1):92–98. doi: 10.1038/bjc.2011.538

Figure 5.

Figure 5

Activity of T cells following priming with VLP-lysate or lysates in the presence or absence of adjuvant. (A) Intracellular IFN-γ staining within CD8+ T cells. (B) Surface CD107 expression on CD8+ T cells. Bars represent specific IFN-γ production or CD107 degranulation on co-culture with Mel888 targets with values against irrelevant SKOV-3 targets subtracted. (C) Cytotoxicity of primed T cells against Mel888 targets labelled with 51Cr. Nonspecific lytic activity against irrelevant 51Cr-labelled SKOV-3 targets has been subtracted. Data represent mean±s.d. for six experiments, *Denotes statistical significance (P<0.05) between VLP-lysate+OK432 and lysate+OK432.