Table 1.

Serum immunoglobulin levels, specific antibody concentrations and avidity indexes in the maternal and cord serum and cord/maternal serum ratios for IgG antibodies from a mother with CVID.

	Maternal	Cord	Placental Transfer ratio (%)
Total Immunoglobulin Concentrations
IgG (mg/dL)	473.0	912.0	190
IgM (mg/dL)	<6.0	12.0	–
IgA (mg/dL)	<3.0	<3.0	–
IgG1 (mg/dL)	362.0	752.0	210
IgG2 (mg/dL)	249.0	192.0	80
IgG3 (mg/dL)	10.0	20.0	200
IgG4 (mg/dL)	6.0	21.0	350
Specific IgG Antibodies Levels
IgG anti-tetanus toxoid (UI/mL)	1.6	3.1	190
IgG anti-Hib PRP* (mg/L)	3.8	3.7	100
IgG anti-PS§1 (mg/L)/avidity (M)+	2.3/>3.0	2.6/>3.0	110
IgG anti-PS3 (mg/L)/avidity (M)	2.4/>3.0	2.8/>3.0	120
IgG anti-PS5 (mg/L)/avidity (M)	7.3/2.7	8.0/2.7	110
IgG anti-PS6 (mg/L)/avidity (M)	6.9/2.7	6.6/>3.0	100
IgG anti-PS9 (mg/L)/avidity (M)	4.4/2.9	4.7/>3.0	110
IgG anti-PS14 (mg/L)/avidity (M)	12.8/2.5	15.0/2.8	120

–IgM and IgA maternal/cord blood ratios were not performed;

*PRP—polyribosyl–ribitolphosphate polymers;

^§Anti-PS—Anti-Streptococcus pneumoniae polysaccharide;

⁺(M) —Avidity index in molarity.