Table 2. Estimated fractions of cancer cases in UK, 2010, attributable to occupational exposures.
Observed cases
|
PAFa
(%) |
Excess attributable cases
|
|||||
---|---|---|---|---|---|---|---|
Cancer site | ICD-10 code | Males | Females | Males | Females | Males | Females |
Nasopharynx | C11 | 267 | 178 | 11 | 2.5 | 29 | 4.5 |
Oesophagus | C15 | 5713 | 2819 | 3.3 | 1.1 | 189 | 31 |
Stomach | C16 | 4467 | 2577 | 3 | 0.3 | 134 | 7.7 |
Liver | C22 | 2270 | 1298 | 0.2 | 0.1 | 4.5 | 1.3 |
Pancreas | C25 | 4084 | 4280 | 0.02 | 0.01 | 0.8 | 0.4 |
Sino-nasalb | C30–31 | 279 | 173 | 46 | 20.1 | 128 | 35 |
Larynx | C32 | 1803 | 386 | 2.9 | 1.6 | 52 | 6.2 |
Lungc | C33 | 22 273 | 18 132 | 20.5 | 4.3 | 4566 | 780 |
Bone | C40–41 | 362 | 256 | 0.04 | 0.01 | 0.1 | 0.0 |
Mesotheliomab | C45 | 2077 | 462 | 97 | 82.5 | 2015 | 381 |
Soft-tissue sarcomab | C49 | 867 | 623 | 3.4 | 1.1 | 29 | 6.9 |
Breast (female) | C50 | — | 48 385 | — | 4.6 | — | 2226 |
Cervix | C53 | — | 2691 | — | 0.7 | — | 19 |
Ovary | C56 | — | 6820 | — | 0.5 | — | 34 |
Kidney | C64–66, C68 | 5697 | 3365 | 0.04 | 0.04 | 2.3 | 1.3 |
Bladder | C67 | 6713 | 2572 | 7.1 | 1.9 | 477 | 49 |
Eyeb | C69 | 210 | 172 | 2.9 | 0.4 | 6.1 | 0.7 |
Brain and CNS | C70–72 | 2799 | 1902 | 0.5 | 0.1 | 14 | 1.9 |
Thyroid | C73 | 602 | 1776 | 0.12 | 0.02 | 0.7 | 0.4 |
Non-Hodgkin lymphoma | C82–85, C96 | 6297 | 5305 | 2.1 | 1.1 | 132 | 58 |
Myeloma | C90 | 2506 | 1994 | 0.4 | 0.1 | 10 | 2.0 |
Leukaemia | C91–95 | 4639 | 3201 | 0.9 | 0.5 | 42 | 16 |
Alld | 158 667 | 155 584 | 4.9 | 2.4 | 7832 | 3662 |
Abbreviations: CNS=central nervous system; ICD=International Classification of Diseases; PAF, population-attributable fraction.
Number of cases estimated from the UK population (2010) and rates in England in 2008.
Lung cancer PAF excludes occupational exposure to environmental tobacco smoke (ETS).
Excluding non-melanoma skin cancer.