Table 1.
Body composition, and muscle mass, strength, and muscle quality in Health ABC participants without and with radiographic knee OA and knee pain (n=858)
| − RKOA, − pain (n=334) |
−RKOA, + pain (n=263) |
+ RKOA, − pain (n=91) |
+ RKOA, + pain (n=170) |
p-value | |
|---|---|---|---|---|---|
| Age (years) | 73.3 (2.7) | 73.3 (2.9) | 73.7 (2.9) | 74.1 (3.1) | 0.008 |
| Gender (n (%) male) | 140 (42) | 110 (42) | 38 (42) | 69 (41) | 0.99 |
| Race (n (%) Black) | 145 (43) | 100 (38) | 52 (57) | 84 (49) | 0.007 |
| NSAID use (n (%), yes) | 181 (55) | 143 (54) | 56 (62) | 105 (62) | 0.22 |
| Physical activity, kcal/week (n(%)) <500 500–999 1000–1499 ≥1500 |
159 (48) 58 (17) 35 (10) 82 (25) |
151 (57) 47 (18) 23 (9) 42 (16) |
49 (54) 10 (11) 10 (11) 22 (24) |
91 (54) 27 (16) 22 (13) 30 (18) |
0.15 |
| BMI (kg/m2) | 26.4 (4.3) | 27.3 (4.4) | 30.5 (5.0) | 30.1 (4.8) | <0.0001 |
| Total mass (kg) | 72.2 (13.3) | 75.4 (14.9) | 83.8 (13.0) | 83.0 (15.5) | <0.0001 |
| Total body lean (kg) | 47.1 (10.4) | 47.8 (10.6) | 52.1 (9.4) | 51.2 (9.7) | <0.0001 |
| Total body fat (kg) | 25.2 (7.6) | 27.6 (8.3) | 31.7 (9.3) | 32.0 (10.0) | <0.0001 |
| Thigh muscle area (cm2) | 108.8 (27.7) | 108.9 (27.7) | 120.5 (27.3) | 116.5 (26.1) | <0.0001 |
| Quadriceps muscle area (cm2) | 51.0 (13.3) | 50.7 (13.0) | 53.6 (13.2) | 51.8 (12.7) | 0.29 |
| Muscle attenuation (HU) | 36.3 (6.9) | 35.0 (6.6) | 33.9 (8.2) | 32.3 (7.1) | <0.0001 |
| Intermuscular fat (cm2) | 9.5 (6.2) | 10.5 (5.8) | 12.4 (6.7) | 12.5 (7.4) | <0.0001 |
| Absolute strength/peak torque (Newton•meters) | 103.2 (34.6) | 102.6 (35.9) | 104.6 (38.3) | 100.0 (35.4) | 0.74 |
| Specific torque (strength/thigh area) | 0.94 (0.20) | 0.94 (0.20) | 0.87 (0.24) | 0.85 (0.19) | <0.0001 |
| Quadriceps specific torque (strength/quad area) | 2.02 (0.41) | 2.01 (0.43) | 1.94 (0.47) | 1.91 (0.41) | 0.02 |
Note: Data are n (%) or means (standard deviations). P-value reflects chi-square test or ANOVA for the difference in means. Radiographic knee OA is defined as KL score ≥ 2 in the same knee for which we have strength (KinCom) and CT data. Knee pain is also for the same knee for which we have strength and CT data.