Skip to main content
. Author manuscript; available in PMC: 2012 Aug 18.
Published in final edited form as: Neurosci Lett. 2011 Jun 29;500(3):212–215. doi: 10.1016/j.neulet.2011.06.043

Figure 2. Paired-pulse facilitation and frequency facilitation are normal in hippocampal slices from APPSwe/PS-1A246E mice.

Figure 2

fEPSPs in hippocampal slices from both wildtype and APPSwe/PS-1A246E mice exhibit robust PPF that was similar across genotypes, as shown in representative experiments (A) and population data (B). Frequency facilitation was elicited using a 1 Hz train of 30 stimuli, and was clearly evident in individual experiments when comparing averages of the first and last 3 fEPSPs (black traces in C) during the train (grey traces in C). Frequency facilitation was similar across genotypes (D).