Table 1. Examples of oocyte maturation defect phenotypes.

Protocol	Phenotype	References	Model parameters	Figures
ablated	MI-entry delay	[8]		Fig. 5A
ablated	MII-entry failure	[4]		Fig. 5A
ablated	MI-entry delay	[5], [8]		Fig. 5B
ablated	Oscillations	[7]		Fig. 5B
ablated	MI-entry failure	[8]	,	Not shown
ablated	MI-entry delay/failure	[22], [40]		Fig. 5C
U0126( inhibitor)	MI/MII failure	[5], [6]		Fig. 5D
overexpressed	MI arrest	[11]		Fig. 5E
ablated	MII-entry failure	[10], [20]		Fig. 5F

Pharmacological or antisense treatments impacting the activity of several specific proteins lead to various sorts of maturation defect phenotypes as reported in the literature. B-type cyclin is abbreviated as Cyc. Changing specific parameters of the model allows to simulate these phenotypes, which is also shown in Fig. 5.